FAT SOLUBILE VITAMINIS
FAT SOLUBILE VITAMINIS
VITAMIN – A
Brand Names: Anti-infective
vitamin; Lard-factor; Axerophthol; Biosterol; Oleovitamin A; Ophthalamin;
Vitamin A; Vitamin A alcohol; Acon; Afaxin; Agiolan; Alphalin; Anatola; Aoral;
Apexol; Apostavit; Atav; Avibon; Avita; Avitol; Axerol; “Dohyfral” A;
Epiteliol; Neo-A-Let; Prepalin; Testavol; Voflol; Vi-Alpha; Vitpex; Vogan;
Vogan-Neu.
Vitamin A occurs in
the animal organism and not in plants. Carotenoids are converted into vitamin A
by the liver. It is extracted from ol. fish liver oils where it occurs mostly
in esterified form.
A suitable form of
retinol (vitamin A alcohol) consists of in esters of edible fatty acids,
principally acetic and palmitic acid. in It is a light yellow to red oil which
may solidify on cooling. It is practically odourless or with a mild fishy
odour, but no rancid ed odour or taste.
Pure vitamin A, m.p.
62-64, occurs as pale yellow plates und or crystals and is insoluble in water
but soluble in alcohol, fixed is oils and usual organic solvents. It is
unstable in the presence of age light and oxygen and in oxidized fats and oils.
Ultraviolet light inactivates vitamin A and its solutions which exhibit a
characteristic green fluorescence. The free alcohol is sensitive to dify
air-oxidation, but oil solutions of it are quite stable. Esters of eS. vitamin
A are more stable to oxidation. In solid form, it may be the dispersible in
water. The vitamin is stored in airtight containers and protected from light.
Uses: Vitamin A is essential for growth, for
the development and maintenance of epithelial tissues, and for vision. Its
deficiency causes night blindness and changes in the skin and mucous membranes.
Vitamin A is used to treat night blindness and skin disorders including acne
and psoriasis.
Side Effect
Intake of excessive
amounts of vitamin A leads toxicity, known as hypervitaminosis which is
characterized by fatigue, irritability, anorexia, loss of weight, vomiting and
other gastrointestinal disorders, fever, skin changes, alopecia, dry hair,
cracking and bleeding of lips, anaemia, headache, pain in bones and joints,
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