PANTOTHENIC ACID

PANTOTHENIC ACID



Brand Names : Chick antidermatitis factor, Vitamin B3


Pantothenic acid, an unstable, viscous oil, extremely hygroscopic, is a factor in the vitamin B complex that is necessary for the proper gowth of animals.


 It is dextrorotatory and is usually marketed as the calcium salt, calcium D (+)- pantothenate. Pantothenic acid occurs every where in animal and plant tissues. The richest common sources are liver, yeast, cereal brans, leafy vegetables diary products and eggs. It may be prepared by the direct condensation off-alanine with lactone of pantoic acid. It is easily destroyed by acids, bases and heat. 


The vitamin is freely soluble in water, ethyl acetate, dioxane, glacial acetic acid; moderately soluble in ether, and amyl alcohol; practically insoluble in benzene and chloroform. One gram of pantothenic acid equals to 70,000-75,000 chick units.



Calcium Pantothenate (Brand Names : Calpanate; Galamila; Pantholin).


Calcium pantothenate, m.p. 195-196° (decomp), occurs as white, odourless, slightly hygroscopic powder. It is soluble in water and glycerol; practically insoluble in alcohol, chloroform and ether; reasonably stable to air and light. Rate of hydrolysis is a function of pH and is catalyzed by the presence ofeletrolytes. Solutions are not stable to autoclaving, and sterilization by filtration is necessary.



Uses : Pantothenic acid is a vitamin B substance. It is a component of co-enzyme A which is essential in the metabolism of carbohydrate, fat, and protein.







Comments

Post a Comment

Popular posts from this blog

PROPANDID

PROPANDID Brand Names : Bayer-1420; FBA-1420; TH-2 180; WH-5668. Propanidid, b.p. 210-212°, is a pale greenish-yellow viscous liquid with a slight odour. It is very slightly soluble in water; miscible with alcohol, chloroform and  ether. Propanidid has been used as an  intravenous anaesthetic for rapid induction and for maintenance of anaesthesia of short duration
Read more

Vitamin A2

Vitamin A2 Vitamin A2, ( Brand Names : Retinol 2; 3,4-Didehydroretino Dehydroretinol); all trans, m.p. 17-19; 13-cis, m.p. 73-74°. is found in marine fishes of the family Labridae and in turtles. It exhibits chemical, physical and biological properties identical to vitamin A Vitamin A2 has about 40 per cent of the bioactivity of crystalline vitamin A
Read more

HOMATROPINE

HOMATROPINE Brand Names : Mandelyltropeine, Tropine mandelate. Homatropine is a synthetic alkaloid which is a lower homologue of atropine. It is prepared by the interaction of tropine and mandelic acid. Homatropine, m.p. 99-100°, occurs as colourless, odourless crystals or a white crystalline powder. It is hygroscopic, but only slightly soluble in water; soluble in alcohol, benzene, chloroform, ether, acetone and dilute acids. The hydrobromide or hydrochloride is obained readily from the free base by neutralizing with hydrobromic or hydrochkoric acid. The hydrobromide occurs as colourless, odourless crystals or a white crystalline powder. It is soluble in water and alcohol; slightly soluble in chloroform; very slightly soluble in ether; stored in airtight containers and protected from light. Homatropine methylbromide, m.p. 210-212°, is the tropine methylbromide ester of mandelic acid. It is prepared by treating homatropine with methyl bromide, thus yielding the ...
Read more