TRICHLOROETHYLENE.

TRICHLOROETHYLENE.

Brand Nanes : Tri-Clene; Trielene; Trilene; Trichloran; Trichloren; Algylen; Trimar; Triline: Tri; Trethylene: Westrosol; Chlorylen; Gemalgene;
Trichloroethylene is usually prepared –
(a) from sym-tetrachloroethane by elimination of hydrochloric acid (by boiling with lime);
 (b) by passing tetrachloroethane vapour over calcium chloride catalyst at 300° or without catalyst at 450*- 47O*, and
(c) by treating acetylene with chlorine in the presence of calcium oxide.

Trichloroethylene is a clear, colourless or pale blue, nonflammable, mobile liquid, b.p. 889, with peculiar odour resembling that of chloroform. It is practically insoluble in water; miscible with ether, alcohol and chloroform, most of fixed and volatile oils. It is slowly decomposed by light in the presence of moisture with formation of HCl. Trichloroethylene for medicinal purposes may contain somethymoland ammonium carbonate (about 100 mg/100 ml) as a stabilizer.

Uses : Trichloroethylene is a weak volatile anaesthetic administered by inhalation; mainly used in short surgical procedures. It is also used as a solvent for fats, waxes, resins, oils, rubber, paints and varnishes; in degreasing in dry cleaning; in the manufacture of organic chemicals, pharmaceuticals such as chloroacetic acid.

Side Effect

The side effects include ventricular arrhythmias, nausea, vomiting and light-headedness. Moderate exposures can cause symptoms similar to alcoholinebriation. Higher concentrations can cause narcotic effect. Deaths occurringafter heavy exposure is due to ventricular fibrillation. Prolonged contact with trichloroethylene can cause dermatitis, eczema, burns and conjunctivitis.






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