AMODIAQUINE HYDROCHLORIDE
Brand Names : CAMAQI;
Camoquin; Flavoquine; Miaquine.
Amodiaquine
hydrochloride occurs as a yellow, odourless bitter crystalline powder, m.p.
150-160°. It is soluble in water; sparingly soluble in alcohol; very slightly soluble
in benzene, chloroform and ether. A 2% aqueous solution has a pH of 3.6 to 4.6.
It is stored in airtight containers.
Uses :
1.
Amodiaquine hydrochloride is an antimalarial
drug which has an action similar to that of chloroquine.
2.
Amodiaquine is highly effective against
Plasmodium vivax and P. falciparum infections, being three to four times as
active as quinine. However, it has no effect on P. falciparum.
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