AMPICILLIN SODIUM

Brand Names :   Sodium amplicillin; Alpen-N-Amcill-S; Cilleral, Domicilin; Omnipen-N; 
                             Pen A/N: Penbritin-S: Penialmen; Polycillin-N; Principen/N; Ampicillinnatrium;                               Ampicillinum Natricum; The sodium salt of amplicillin.



It occurs as a white to off-white odourless, crystalline or amorphous, hygroscopic powder; decomposes at about 205. It is soluble in water (1 in 2) and acetone (1 in 50); slightly soluble in chloroform, practically insoluble in ether, liquid paraffin, and fixed oils). It is stored at a temperature not exceeding 25° in well closed container .


Stability of Ampicillin sodium in aqueous solutions is enin; dependent on many factors including concentration, pH, S; temperature and the nature of the vehicle. Stability decreases significantly in the presence of glucose, fructose, invert sugar, dextrans and lactate.


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