ANALGESICS AND ANTIPYRETICS
ANALGESICS
Analgesics
are the agents which relieve pain without causing loss of consciousness. They
are generally used for the relief of noderate to severe pain. The main
analgesic agents are morphine and related compounds and some totally synthetic
agents, e.g., butorphanol, pentazocine, methadone, etc.
Antipyretics
If
the body core temperature rises by more than a few degrees in man, then mental changes
occur. The commonest manifestation of a change incore temperature is fiver. The
hypothalamus plays an important role in thermo-regulatory responses of the
body. It controls the body temperature by an increase in sweat gland activity.
Many diseases can give rise to fever, the commonest being infection. The
increase in temperature is caused by the hypothalamus which reduces heat loss
by peripheral vasoconstriction and increases heat production by shivering.
Antipyretics are the agents which reduce the body temperature in febrile state.
Aspirin, paracetamol and analgin are some antipyretics.
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