ANTI-FUNGAL AGENTS

Fungal infections are due to poor host resistance and are now common worldwide. Antifungal agents are used to treat various fungal infections of hair, mucous membranes, nails, or skin. The fungi of the genera Candida (Co is). Epidermophyton. Microsporum and Trichophyton (tinea. ringworm) produce fungal infection. The systemic fungal infections include localized or disseminated blastomycosis, cryptococosis, candidiasis and other invasive infections. Antifungal agents are employed locally, e.g. antibiotics (nystatin, pimaricin, hamycin) or they may be employed systematically, e.g. antibiotics (griseofulvin, amphotericin B), azole derivatives and flucytosine. Fatty acids in perspiration have been found to be fungistatic.

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