ASPIRIN

Brand Names : Acenterine; Aceticyl; Acetophen; Acetosal; Acetosalin; Acetylin; Acetyl-SAL; Acimetten; Acylpyrin; A.S.A.; Asatard; Aspro; Asteric; Caprin; Colfarit; Contrheuma retard; Delgesic; Duramax; Ecotrin; Empirin; ECM; Endydol; Entrophen; Enterosarine; Helicon; Neuronika; Rhodine; Salacetin; Salcetogen; Saletin; Solpyron; Xara.

Aspirin is prepared by the action of acetyl chloride or acetic anhydride on salicylic acid.



Aspirin, m.p. 135°, is a colourless, odourless, crystalline powder which is soluble in water (1:300), alcohol (1:6), chloroform (1:17) and ether. It is stable in dry air, but gradually hydrolyses in contact with moisture to acetic and salicylic acids. It is decomposed in boiling water or when dissolved in solutions of alkali hydroxides and carbonates.



Uses: Aspirin has analgesic, anti-inflammatory and antipyretic properties. It is used for the relief of pains such as headache, dysmenorrhoea, myalgias and toothache. It is also used in inflammatory disorders such as rheumatoid arthritis and to treat colds and influenza.


Side Effect


The most common adverse effects with aspirin therapy are gastro-intestinal disorders such as nausea, dyspepsia and vomiting, irritation of gastric mucosa and increasing in bleeding time.

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