BIPERIDEN

Brand Names : Akinetion; KL. 373.


Biperiden, m.p. 112-116°, is a white, odourless, crystalline powder. It is freely soluble in chloroform and methanol; sparingly soluble in alcohol; practically insoluble in water.

Biperiden hydrochloride (Brand Names; Kineton; Akinophyl). m.p. 275 (dec), is a white, odourless, optically inactive, crystalline powder. It is slightly soluble in water, alcohol, chloroform, and ether; sparingly soluble in methanol; stored in airtight containers and protected from light.

Uses :

Biperiden is anticholinergic, antimuscarinic and antiparkinsonian agent used to treat all types of parkinosonism, to alleviate the extrapyramidal syndrome induced by drugs, and to eliminate akinesia, rigidity and tremor.

Side Effect
Side effects of biperiden and other antimuscarinic agents include dryness of mouth, thirst, dilation of the pupils, flushing and dryness of the skin, bradycardia, reduction of tone, constipation, etc. Sometimes vomiting, giddiness and staggering may occur. Toxic doses cause tachycardia, rapid respiration, hyperpyrexia and CNS stimulation.


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