BUSULPHAN

Brand Names : Methanesulphonic acid tetramethylene ester; CB-2041; GT 41: Misulban; Mitosan; Myleran; Myelosan; Myeleukon; Myelolukon; Sulfabutin; Meilucin.

Busulphan, m.p. 114-118°, is a white crystalline powder. It is sparingly soluble in water, but dissolves slowly as hydrolysis takes place; soluble in alcohol and acetone. It is stored in airtight containers and protected from light.



Uses:. Busulphanis an antineoplastic agent and has depressant action on bone marrow. It is used in the palliative treatment of chronic granulocytic leukaemia


Side Effect


The most important side-effects of busulphan in high olutions dosage are leukopenia, thrombocytopenia and haemorrhage to symptoms


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