CHINIOFEN

Brand Names : Anayodin Quinoxyl, Yatren.

It is prepared by sulphonating 8-hydroxyquiniline, subjecting the product to potassium iodide and bleaching powder in the presence of potassium carbonate, precipitating the derived

phenol with hydrochloric acid and finally, mixing with sodium carbonate.

Chiniofon is a mixture of 7-iodo-8-hydroxyquinoline-5- sulphonic acid, its sodium salt and sodium carbonate containing about 26-29 per cent of iodinelt is a canary-yellow powder with a slight odour, a bitter taste producing a sweet sensation later on. On adding to water, it effervesces due to reaction with the sodium carbonate and finally dissolves. It forms deep, emeraldgreen colour with dilute ferric chloridesolution and a dense, white precipitate with copper sulphate

Uses

Chiniofon is used to cure amoebic dysentery, as a surgical dusting powder and in gonorrhoea and diphtheria.

Halquinol : It is a mixture of 5,7-dichloro-8-hydroxyquinoline (57-74%), 5-chloro-8-hydroxyquinoline (23-40%) and 7-chloro8-hydroxyquinoline (4%). Halquinol is a yellow-white voluminous powder with a faint cresol-like odour; insoluble in water; soluble in most organic solvents. It is protected from light and kept away from metals. Halquinol is antiamoebic, antibacterial and antifungal. It is used to treat bacterial and amoebic dysentery and in skin diseases.