CHLORPROMAZINE HYDROCHLORIDE



Brand Names : Hebanil; Hibanil; Hibernal; Klorpromex, Largactil; Largaktyl; Megaphen; Promacid; Chloractil; Chlorazin; Sonazine; Torazine; Torazina; Marazine; Propaphenin; Taroctyl.



It is an odourless, white or creamy-white crystalline powder, othiazine- m.p. 179-180°. It decomposes on exposure to air and light nopropyl) becoming yellow, pink, and finally violet. It is soluble in water (1 in 0.4), alcohol (1 in 1.3) and chloroform (1 in 1); practically 26O1-A; insoluble in ether and benzene; slightly acidic to litmus; stored in airtight containers and protected from light.

Uses:



Chlorpromazine has sedative, anti-emetic, antipruritic, Aminazine; sęda serotonin-blocking and weak antihistaminic properties. It is used in the management of psychotic conditions, to control hyperkinetic states . It controls excitement and agitation. It is anti-emetic and is used to control the nausea and vomiting The phenothiazines and related neuroleptic produce a - lesser degree of central depression than the barbiturates or quantity of benzodiazepines. The adverse effects of phenothiazine include dryness of mouth, constipation, urinary retention and mydriasis.




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