CISPLATIN


Brand Names : cis-Platinum II; cis-DDP; CACP; CPDC; DDP; NSC-1 19875; Cisplatyl; Neoplatin; Platinex; Platinol

It occurs as deep yellow solid, m.p. 270* (decomp). It is insoluble in most common solvent and is changed to trans-form in aqueous solution. Aqueous solutions are stable for 24 hours at room temperature. It is not necessary to prepare a solution immediately before use provided it was protected from light.



Uses: Cisplatin is used in the treatment of metastatic tumours of testes, ovary and bladder..

Side Effect

Severe nausea and vomiting occur in most patients during treatment with cisplatin. Serious toxic effects on kidney, bone marrow, and ears have been reported.



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