CLOFIBRATE



Brartad Names : Amotril; Anparton; Apolan; Artevill; Ateculon; Ateriosan; Atheropront; Atromidin; . Atromid-S; Bioscleran; Claripex: Cloberate: Clobren-SF; Clofinit; CPIB; Hyclorate; Lipawlon; Liprinal; Neo-Atromid; Normet; Normolipol; Recollip; Regelan; Serotinex; Sklerolip; Skleromexe; Sklero-Tablinen; Ticlobran; Xyduril.



Clofibrate, b.p. 148-150°, is a stable, clear, colourless to pale yellow liquid with a characteristic  faintly acrid odour. It is very slightly soluble in water; miscible with alcohol, chloroform and ether; stored in airtight containers and protected from light.



Clofibrate is readily hydrolyzed by serum enzymes in gastrointestinal tract to yield free acid. It is effective in lowering serum triglycerides.



Uses : Clofibrate is used as a hypolipidaemic agent and for the prophylaxis of ischaimic heart disease.



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