DEXTRO AMPHETAMINE SULPHATE

DEXTROAMPHETAMINESULPHATE

Brand Names : Dexedrine sulphate; Afatin; Dexamphetamine, Dexampex; ( ) —CH CH---CH3 d-Amfetasul; Domafate; Obesedrin; sh Dexten; Maxiton; Sympamin; Nнг “2 Albemap; Dadex; Adrex; Dexalone; Amsustain; Betafedrina; Diocurb; Amphetamine sulphate.


Dextroamphetamine (Amphetamine) 

It is a mobile, colourless with liquid amine-like odour and acrid burning taste, b. p. 200-2O3*.
Amphetamine is a strong base and forms an alkaline solution in water. It contains an asymmetric carbon atom, and the synthetic compound is the (t) - mixture. It is resolved by fractional crystallization of the D-tartrates followed by treatment with 10% HSO. It may be prepared from phenylalanine. Dextroamphetamine sulphate, the dextrorotatory isomer of amphetamine, is a white, odourless, crystalline powder; m.p. 300* soluble in water (1 in 10) and alcohol (1 in 800); practically insoluble in ether; stored in well-closed containers .


Uses : Dextroamphetamine is a sympathomimetic agent with adrenergic activity. It has marked stimulant effect on the central nervous system.

Side Effect

The side-effects of dexamphetamine are overstimulation of the central nervous system, insomnia, nervousness, restlessness, irritability and euphoria. Excessive use may lead to tolerance and physical dependence.






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