DEXTROPROPOXYPHENE HYDROCHLORIDE
Brand Names: Algafan; Antalvic; Darvon; Depromic; Doloxene;
Deprancol; Develin; Dolene; Dolocap; Doraphen; Erantin; Femadol; Harmar;
Propox; Propoxychel; Proxagesic);
It's m.p. 1631699, is a white or slightly yellow
odourless powder. It is soluble in water, alcohol, chloroform and acetone;
practically insoluble in benzene and ether. It is kept in airtight containers.
The analgesic potency of dextropropoxyphene is almost equal to
codeine phosphate and exhibits fewer side-effects. It has no antidiarrhoeal,
antitussive or antipyretic effect like most of the other analgesic agents. It
is not much effective in deep paln.
Uses: Dextropropoxyphene is an analgesic related to methadone. It
is mainly used in conjunction with other analgesics with antiinflammatory and
antipyretic effects.
Adverse Effect
Adverse effects of dextropropoxyphene are the same as for
morphine. Gastro-intestinal effects are the most common. Liver impairment has
been reported.
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