ISOPRENALINE

ISOPRENALINE

Brand Names : A-2 l; Aludrine; Aleudrin; Isuprel; Norisodrine; Asiprenol; Asmalar; Neo-Epinine; Novodrin; Isupren; Neodrenal Lomu pren, Isopropydrin; Assiprenol; Respifral; Bellasthman; Saventrine; Proternol; Isorenin; . Vapo-N- Iso; Isonorin; Isoproterenol; Isopropylarterenol.

Isoproterenol hydrochloride, m.p. 170-1719, is a white. odourless, crystalline powder. It gradually darkens on exposure to air and light. It is soluble in water and alcohol: practically insoluble in chloroform, ether and benzene, its aqueous solutions become pink on standing. It is stored in airtight containers and protected from light. -

The presence of a larger alkyl (isopropyl) group on the anino group eliminates circulatory effects except palpitation of the heart.

Uses : Isoproterenol is a sympathomimetic agent, chiefly as bronchodilator. It stimulates the central nervous system. It has a powerful stimulating action on the heart and increases cardiac output and rate. It also causes peripheral vasodilation and produces a fall in diastolic blood pressure.

Side Effect

 Prolonged use of isoprenaline may lead to Ir resistance, eventual deterioration and severe damage to the teeth