L-METHYLDOPA

L-METHYLDOPA

Brand Names : AMD; MK-351; Aldomet; Aldometil; Aldomine; Dopemet; Dopegyt: Dopatec; Medomet; Medopa; Medopren; Methoplain; Sembrina; Presinol.

Methyldopa, m.p. 292-293, is a colourless or white to yellowish-white odourless fine powder which may contain friable lumps. It is slightly soluble in water and alcohol; practically insoluble in chloroform and ether; dissolves in dilute mineral acids; protected from light.

Uses : Methyldopa is an antihypertensive agent. It reduces the standing blood pressure and supine blood pressure.

Methyldopate hydrochloride is used in pharmaceutical dosage forms.

Side Effect

The most commonside-effect is drowsiness. Other common side-effects include depression, psychic effects, impaired mental acuity, nightmares, nausea, dryness of the mouth, nasal stuffiness, weakness, dizziness, light headedness, headache, oedema and disorders of sexual function.