MANNITOL

MANNITOL

Brand Names : Mannite; Manna sugar; Cordycepic acid; Manicol; Mannidex; Diosmol; Osmitirol; Osmosal;

Mannitol, m.p. 166-168°, is a white, odourless crystalline powder or granules with a sweet taste. It is soluble in water; slightly soluble in alcohol and pyridine; practically insoluble in ether; soluble in solutions of alkali carbonates and hydroxides.


Uses : Monnitol is diuretic used to increase urine flow in patients with acute renal faliure  to reduce intra-ocular pressure prior to ophthalmic procedures, to promote the excretion of dis toxic substances by forced diuresis, as diluent and excipientin in pharmaceutical preparations, as a bulk "sweetener, for determination of the glomertular filtration-rate, to treat patients with renal failure.
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In industry mannitol is used with boric acid in the manufacturing of dry electrolytic condensers for radio applications; In making artificial resins and plasticizers; in analytical chemistry for boron determination; as anticalking and free-flow agent, flavouring agent, lubricant and release agent, stabilizer, thickener and nutritive sweetener.




Side Effect


The most common side effects associated with mannitol therapy are fluid and electrolyte imbalance, circulatory overload, acidosis, diarrhoea, nausea, vomiting, thirst, headache, dizziness, chills, fever, etc.



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