METFORMIN

METFORMIN





Brand Names : DMGG; La 6023: Diabetosan; . Diabex; Fluamine; Flumamine; Gliguanid.




Metformin hydrochloride, m.p. 218-220°, (Brand Names: Diabefagos, Glucophage, Haurymellin; Meguan; Metiguanide) 

It is a white, odourless, hygroscopic, crystalline powder; soluble in water and alcohol; practically insoluble in chloroform and ether; stored in airtight containers.

Uses: Metformin is used in non-insulin dependent dia-betes mellitus when diet control fails. It has been reported to increase blood-lipid concentrations.

Side Effect

Metformin causes gastro-intestinal adverse effects with anorexia, nausea, and vomiting. Lactic acidosis has occurred but to a lesser extent than phenformin.




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