METHYLTHIOURACIL

METHYLTHIOURACIL




Brand Names : MTU; Alkiron; Antibason; Basecil; Basethyrin; Methiacil; Methicil: Methiocil: Muracil: Prostrumyi: Strunacil; Thimecil; Thyreostat I



Methylthiouracil is a homologue of thiouracil synthesized by condensing thiourea with sodium derivative of ethyl acetoacetate:



Methylthiouracil, m.p. 326-3319 (decomp), is a white odourless crystalline powder which is soluble in boiling water; sparingly soluble in alcohol, chloroform and ether; freely soluble in ammonium hydroxide and in solutions of alkali hydroxides. 



A saturated aqueous solution is neutral or slightly acidic to litmus. It is protected from light and stored is well-closed containers.


Uses : Methylthiouracilis an antithyroid agent which has been used in the treatment of hyperthyroidism.

Side Effect

The common side effects include nausea, vomiting, gastric distress, headache and skin rashes.


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