NITROFURANTOIN

NITROFURANTOIN



Brand Names:              Berkfurin; Berkfuran; Chemiofuran; Cyantin; . Cystit; Fua-Medi; Furachel;                                         Furalan; Furadantin; Furadantine MC; Furadoine; Furadonine; Furantoin;                                         Furobactina; Furophen; Ituran; Macrodantin; Orafuran; Parfuran; Trantoin;                                       Urantoin; Urizept; Urodil; Urodin: Urolong Uro-Tablinen; Welfurin; Zoofurin.




It occurs as yellow odourless or almost odourless crystals or fine powder with a bitter after taste, m.p. 270-272°(dec). 


It is discoloured by alkalis and by exposure to light. It is very slightly soluble in water and alcohol; soluble 1 in 16 of dimethylformide.

 It is stored at a temperature not exceeding 25 in airtight containers and avoid contact with metal other than stainless steel or aluminium; protected from light.


Uses

1.    Nitrofurantoin is used in the treatment of uncomplicated lower urinary tract infection and for long-term suppressive therapy.
2.     It has been effective for infections that were resistant to antibiotics. Few side-effects, such as diarrhoea, pruritus or crystalluria, have been observed.

Side effect


The most common side effect of nitrofurantoin is with gastro-intestinal tract causing nausea, vomiting, anorexia, and abdominal pain




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