OXYTETRACYCLINE HYDROCHLORIDE

OXYTETRACYCLINE HYDROCHLORIDE




Synonyms : Aquacycline; Arcospectron; Bio-Mycin; Duphacycline: Geomycin; Gynamousse; Imperacin (Capsules); Macocyn; Macodyn; Occrycetin; Oxlopar; Oxybiotic; Oxybiocycline; Oxycycline; Oxyject; Stecsolin; Tetra-Tablinen; Toxinal: Terramycin; Tetramel HCl; Ryomycin HCl.



The oxytetracycline antibiotic substance has been  isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. 



It occurs as a pale yellow or yellow or light brown, hygroscopic, stable crystalline powder with a bitter taste. It is soluble in water (1 in 2), alcohol (1 in 45); solubel ,  practically insoluble in chloroform and ethery Concentrated Sta aqueous solutions at neutral pH hydrolyze of standing and for deposit crystals of oxytetracycline and the solutions become by turbid. Oxytetracycline hydrochloride is inactivated rapidly by deterioration in solutions having a pH of less than 2 and is e rapidly destroyed by alkali hydroxide solutions.
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 The amphoteric base and the hydrochloride are absorbed rapidly from the digestive tract readily. Oxytetracycline is stored in airtight hv containers and protected from light.

Uses:


Oxytetracycline has the same antimicrobial activity and  uses as tetracycline hydrochloride. It is usually used in tablets, the calcium salt in aqueous oral suspensions,  and the hydrochloride in capsules and intravenous injections.



Comments

  1. alfachemistryAugust 31, 2018 at 7:10 AM

    A synthetic derivative of oxytetracycline. Acts as a broad spectrum antibiotic and matrix metallo-proteinases (MMP) inhibitor. Useful in studies involving wound healing and tissue remodeling. Doxycycline Hyclate

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