PRALDOXME CHLORIDE

PRALDOXME CHLORIDE






Brand names : 2-PAM Chloride; Protopam Chloride






Pralidoxime chloride is 2-formyl-l-methylpyridinium chloride oxime. It is white or pale yellow, odourless crystalline powder; freely soluble in water, m.p. 235-238°.







 Uses: Pralidoxime chloride is used as cholinesterase reactivator: as antidote for poisoning by parathion and related pesticides. It is anticholinergic, cholinomimetic, it inhibits cholinesterase, and potentiates the depresser action of acetylcholine. It is most effective by intramuscular, subcutaneous or intravenous administration.

Adverse Effect


Adverse effects of pralidoximine are drowsiness, dizziness, disturbances of vision, nausea, tachycardia, headache, hyperventilation and muscular weakness.



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