PROCANAMIDE HYDROCHLORIDE

PROCANAMIDE   HYDROCHLORIDE




Brand Names : Procainamide hydrochloride; Amidoprocain; Novocamid; Novocainamid; Procamide; Procan-SR; Procapan; Procardyll; Promide; Pronestyl hydrochloride; Supicaine amide hydrochloride.



Procainamide hydrochloride m. p. 165-169°, is a white to tan coloured, odourless, hygroscopic, crystalline powder. It is freely soluble in water; soluble in alcohol; slightly soluble in chloroform; very sparingly soluble in benzene and ether. The pH of a 10 percent solution is 5.5. Commercially available aqueous solutions are preserved with 0.9 per cent benzyl alcohol and 0.09 per cent of sodium bisulfite. The drug is stored in airtight containers.


Uses : Procainamide is cardiac depressant used for the acute control of arrhythmias to maintain sinus rhythm after cardioversion of atrial fibrillation, to treat arrhythmias and extrasystoles and correct cardiac arrhythmias during anaesthesia.




Side effect

Cardiac effects, hypersensitivity, anorexia, nausea, vomiting, bitter taste, and diarrhoea are the common side effects of procainamide therapy.








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