PROPANTHELINE BROMIDE

PROPANTHELINE BROMIDE

Brand Names : Corrigast, Ercotina; Giquel; Pro-Banthine; Prodixamon; Ketaman; Neo-metantyl; Pantheline;

Propantheline bromide, m.p. 159-161°, is a white or yellowish-white odourless, hygroscopic powder. it is very soluble in water, alcohol and chloroform; practically insoluble in ether and benzene; stored in well-closed containers.

Uses: Propantheline bromide is an antimuscarinic agent with peripheral effects similar to those of atropine. It is used in the treatment of peptic ulcer, gastritis, acute pancreatitis, enuresis. hyperhidrosis and spasm of the gastro-intestinal, biliary and urinary tracts.




Side Effect



Side effects of propanthelene bromide and other antimuscarinic agents include dryness of mouth, thirst, dilation of the pupils, flushing and dryness of the skin, bradycardia, reduction of tone, constipation, etc. Sometimes vomiting, giddiness and staggering may occur. Toxic doses cause tachycardia, rapid respiration, hyperpyrexia and CNS stimulation.




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