RAUWOLFIA ALKALOIDS

RAUWOLFIA ALKALOIDS




Synonyms : Chotachand, Rauwolifia; Rauwolifia serpentina; Raudixin; Rauserpa; Rauvel.




Rauwolfia is the powdered whole root of Rauuvolfia serpentina (Apocynaceae). It contains not less than 0.15 per cent of reserpinerescinnamine group alkaloids calculated as reserpine. This is a small shrub native to the Orient from India to Sumatra. It contains many indole alkaloids, e.g., reserpine, resespinine, yohimbine, ajmaline, serpentine and respentinine. 


The most active as hypotensive agents being the ester alkaloids, reserpine and rescinnamine. The drug is stored at 15° to 30° in a dry place.




Rauwolfia powder is a light-tan to light-brown powder, sparingly soluble in alcohol and only slightly soluble in water. It contains the total alkaloids, reserpine being about 50 percent of the total activity. Extracts are sold under trade names, such as Austrawolf, Egalin, Gendon, Hiwolfia, Koglucoid, Ralfen, Raucolyt. Raudixin, Raulfin, Raurixin, Rauserpol, Rautensine, Rauverid, Rauvilloid, Ra-Valeas, Rauwoldin, Rawotal, Rivadescine, Roxinil, Sarpagan. Serpina. Wolfin.


 Uses : Rauwolfia is used as an antihypertensive agent.


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