TALAZOLINE

TALAZOLINE





Brand Names: Benzazoline; Phenylmethylimidazoline; Priscoline; Priscol; Vasodil; Prefaxil; Benzidazol; Vasimid; Kasimid; Artonil; Vasodilatan; Lambril; Olitensol.



Tolazoline hydrochloride, m.p. 1749, is a white or creamy white, bitter, crystalline powder with slight aromatic odour. It is soluble in water (1 in l), alcohol (l in 2), chloroform (l in 3); practically insoluble in ether. Aqueous solutions are slightly acidic to litmus. The drug is stored in well-closed containers.




Uses: 


Tolazoline is an anti-adrenergic, and vasodilator; used to reduce pulmonary artery pressure and in the treatment of peripheral vascular disorders, acrocyanosis, arteriosclerosis obliterans, Buerger's disease, Raynaud's disease, frostbite sequelae, thrombophlebitis, etc.




Side Effect




Common side effects of tolazoline include pilo-erection. headache, flushing, tachycardia, cardiac arrhythmias, tinging, chilliness, shivering, sweating, nausea, vomiting, diarrhoea and epigastric pain

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