TOLNAFTATE

TOLNAFTATE







Brand Names : Naphthiomate T: Sch 10144; Aftate; Chinofungin; Focusan; Hi-Alazin; Sporiline; Tinactin; Tinaderm; Tonofal.

Tolnaftate is an O-ester of O thiocarbanilic acid; the carbanilic acid being phenylcarbamic acid. It is a white to creamy-white fine powder, odourless or with a slight odour, m.p. 110-112°: practically insoluble in water; sparingly soluble in methanol and ethanol; soluble in chloroform. acetone and carbon tetrachloride; stored in airtight containers.

Uses : Tolnaftate is an antifungal agent used topically as a 1% solution, powder, or cream in the treatment of tinea infections and of pityriasis versicolour. It is used with nystatin when candidal infections are present.

Side Effect
Skin reactions including irritation and pruritus may occur; contact dermatitis has been reported.



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