TROPICAMIDE

TROPICAMIDE

Brand Names : Bistropamide; Mydriacyl.

Tropicamide m. p. 96-97°, is a synthetic derivative of the amide of tropic acid. It is a white, odourless, crystalline powder, - slightly soluble in water; soluble in alcohol and chloroform; freely soluble in solutions of strong acids. Solutions for ophthalmic use have a pH of 4.0 and 5.0.Tropicamide is stored in airtight containers and protected from light.

Uses : Tropicamide is anticholinergic (ophthalmic), and antimuscarinic agent with actions similar to those of atropine. Its action is more rapid in onset than other mydriatics.

Side Effect
Side effects of tropicamide and other antimuscarinic agents include dryness of mouth, thirst, dilation of the pupils, flushing and dryness of the skin, bradycardia, reduction of tone, constipation, etc. Sometimes vomiting, giddiness and staggering may occur. Toxic doses cause tachycardia, rapid respiration, hyperpyrexia and CNS stimulation.






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