UNDECYLENIC ACID

UNDECYLENIC ACID


Brand Names : Declid; Renselin; Sevinon; Acidum; Undecylenicum.
It consists mainly of undec-10-enoic acid and occurs in Sweat.

t is prepared by vaccum distillation of castor oil in which pyrolysis of ricinoleic acid takes place. It occurs as a colourless or pale yellow clear liquid or a white to pale yellow crystalline mass with a characteristic odour like perspiration and a bitter or acrid taste.

Undecenoic acid is practically insoluble in water; freely soluble in alcohol, chloroform, ether and fixed and volatile oils; m.p. 24.5°. It is stored in airtight containers at a temperature of 8 to 15°; protected from light.

Zinc Undecylenate : It is a fine white powder; practically insoluble in water, alcohol, and ether, m.p. 115-116°. It can be prepared by dissolving zinc oxide in dilute undecylenic acid and concentrating the solution. It is stored in well-closed containers and protected from light.

Uses:
 Undecenoic acid and its zinc salt are applied topically in the prophylaxis and treatment of dermatophytic infections of superficial areas. Undecenoic acid is applied to the skin in concentrations of 2% to 10%, and zinc undecenoate in concentrations of up to 20%. They are used in creams, ointments, or powders, often in conjunction with other. Internally, a very pure form is used in capsules to cure psoriasis and neurodermatitis.

Side Effect

Irritation may rarely occur after the topical application of undecenoic acid or its salts.





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